By Vimal K. Sharma, John R. M. Copeland (auth.), Karabi Ghose (eds.)
Depression is likely one of the most common difficulties in previous age. but until eventually lately, outdated humans have been systematically exduded from partaking in drug trials and comparable investigations. for this reason, wisdom concerning prevalence, average heritage and administration of melancholy within the aged are just a little constrained. it really is now well-established that previous individuals are delicate to so much psychotropic medicinal drugs they usually are likely to be afflicted by adversarial results and negative effects of antidepressant medications extra usually than the other age staff. those are thought of to be because of age-related physiological adjustments. additionally, as a result common organization with a number of pathology, the aged are inclined to obtain polypharmacy which additional complicates the administration of antidepressant drug treatment. the purpose of this ebook is to supply a entire suggestions at the drug remedy of melancholy for the dinicians occupied with the overall healthiness care of the aged. within the first part, epidemiology, shows and evaluation of melancholy in outdated age and neuroendocrine abnormalities saw in sufferers with melancholy are in brief mentioned. although, it almost always offers with the issues of antidepressant drug treatment, akin to which antidepressant to prescribe, the right way to visual display unit efficacy and unwanted effects, what's the sufficient dose, how lengthy to regard a unmarried episode of melancholy and who calls for long-term drugs. information about pharmacology, unwanted side effects, opposed results, drug interplay and pharmacokinetics of so much at present to be had medicines are supplied. distinctive emphasis has been given on continuation treatment and the alternative of an antidepressant drug and their long-term safety.
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1985) The dexamethasone supression test and depressive signs in dementia. J. Aff. , 8, 83. , Beamish, P. and Roth, M. (1964) Old age mental dis orders in Newcastle-upon Tyne. Brit. J. , 110, 146. K. and Bergmann, K. (1980) Epidemiology ofmental dis orders among the aged in the community. In: Handbook of Mental Health and Ageing (eds. E. B. Slone), Prentice-Hall, Englewood Cliffs, pp. 34-56. , Scott, R. et al. (1985) Dementia and depression 41 Epidemiology and natural history of depression among the elderly living in the Hobart community: the effect of the diagnostie criteria on the prevalence rates.
Whether or not still further increases in suicide rate in old age are to be predicted, it is clear that, as Shulman (1978) points out, although less than 15% of the population of most Western countries is aged 65 and over, up to 30% of suicides occur in the over 65s. A number of studies have investigated retrospectively the characteristics of elderly successful suicides. Barraclough (1971) found that 26 out of 30 elderly suicides were clearly mentally ill. All had depressive illnesses, though in seven the depression was associated with terminal physical illness, alcoholism or acute confusion.
J. , 110, 146. K. and Bergmann, K. (1980) Epidemiology ofmental dis orders among the aged in the community. In: Handbook of Mental Health and Ageing (eds. E. B. Slone), Prentice-Hall, Englewood Cliffs, pp. 34-56. , Scott, R. et al. (1985) Dementia and depression 41 Epidemiology and natural history of depression among the elderly living in the Hobart community: the effect of the diagnostie criteria on the prevalence rates. Psychol. , 15, 771. A. (1983) The relationship between senile dementia (Alzheimer type) and depression.