By Jeremy M. Berg, John L. Tymoczko, Lubert Stryer
Within the re-creation of Biochemistry, teachers will see the the entire hallmark beneficial properties that made this a constant bestseller for the undergraduate biochemistry path: extraordinary readability and concision, a extra organic concentration, state-of-the-art content material, and a sublime, uncluttered design. complete in either the study room and the laboratory, coauthors Jeremy Berg and John Tymoczko draw at the field’s dynamic study to illustrate its basic principles.
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Extra resources for Biochemistry (Looseleaf)
3). 11). 11. RNA and DNA Compared. Removal of the 2’-hydroxyl group from RNA to form DNA results in a backbone that is less susceptible to cleavage by hydrolysis and thus enables more-stable storage of genetic information. What is the selective advantage of DNA over RNA as the genetic material? The genetic material must be extremely stable so that sequence information can be passed on from generation to generation without degradation. RNA itself is a remarkably stable molecule; negative charges in the sugar-phosphate backbone protect it from attack by hydroxide ions that would lead to hydrolytic cleavage.
4. RNA Template-Directed Polypeptide Synthesis Links the RNA and Protein Worlds Polypeptides would have played only a limited role early in the evolution of life because their structures are not suited to self-replication in the way that nucleic acid structures are. However, polypeptides could have been included in evolutionary processes indirectly. For example, if the properties of a particular polypeptide favored the survival and replication of a class of RNA molecules, then these RNA molecules could have evolved ribozyme activities that promoted the synthesis of that polypeptide.
Removal of the 2’-hydroxyl group from RNA to form DNA results in a backbone that is less susceptible to cleavage by hydrolysis and thus enables more-stable storage of genetic information. What is the selective advantage of DNA over RNA as the genetic material? The genetic material must be extremely stable so that sequence information can be passed on from generation to generation without degradation. RNA itself is a remarkably stable molecule; negative charges in the sugar-phosphate backbone protect it from attack by hydroxide ions that would lead to hydrolytic cleavage.